A Paradigm Shift in Nonalcoholic Fatty Liver Disease Management
Learn about Non-alcoholic liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH), the current management options, and potential future treatments.
About this course
Non-alcoholic liver disease (NAFLD) is the most common cause of liver disease in the United States and is associated with significant morbidity and mortality once NALFD progresses to non-alcoholic steatohepatitis (NASH). NASH is predicted to become the main indication for liver transplant in the United States as obesity rates continue to rise. Currently, management of NAFLD is limited to lifestyle modifications with pharmacotherapy gaps. Once NAFLD has progressed to NASH, the use of off-label medications including thiazolidines and vitamin E can be considered. However, in recent years, GLP-1 agonists and SGLT-2 antagonists have demonstrated efficacy in reversing hepatosteatosis and fibrosis in several studies in NAFLD and early NASH. Additionally, several novel agents are in phase III clinical studies for the treatment of NASH. The scope of treatment of NAFLD and NASH is likely to change dramatically in the next decade as the burden of disease increases.
Course Accreditation
This course is approved for the following professions. You can get more details on each profession by clicking on it.
Instructors
Dr. Guirguis attended Palm Beach Atlantic University for her Doctor of Pharmacy degree then pursed a pharmacy practice residency at the Miami Veterans Affairs Hospital in Miami, Florida. After completing residency, she pursued board certification in pharmacotherapy and is currently an associate professor of pharmacy practice at Palm Beach Atlantic University with expertise in internal medicine. Her teaching responsibility include coordinated and teaching a special populations pharmacotherapy course as well as teaching liver diseases in the Gastrointestinal and Renal Pharmacotherapy course. As an internal medicine faculty member, she has been practicing in internal medicine with an interdisciplinary team at several teaching hospitals for over 10 years. Additionally, she is involved in research and has published several review articles on off-label use of medications as well as other internal medicine pharmacotherapy topics.
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